论文部分内容阅读
目的为预防维和部队官兵执行任务期间发生霍乱疫情,观察口服重组B亚单位/菌体霍乱疫苗(肠溶胶囊)的免疫学效果。方法维和部队官兵184人,分别在0、7、28d口服疫苗一粒,并在0、1、2、8个月采集血标本,检测血清IgG抗体。结果口服霍乱疫苗后不良反应发生率为3.26%,0、1、2、8个月血清抗体阳性率分别为:7.06%、54.34%、76.09%、39.13%;执行任务的8个月未发现霍乱疫情。结论口服霍乱疫苗后,维和官兵血清抗体水平有较大的提高,对霍乱有一定的预防作用。
Objective To observe the immunological effects of oral recombinant B subunit / mycobacterial cholera vaccine (enteric-coated capsules) in order to prevent the occurrence of cholera outbreak during the mission of the peacekeepers. Methods A total of 184 officers and soldiers of peacekeeping force were given oral vaccine at 0, 7 and 28 days respectively. Blood samples were taken at 0, 1, 2 and 8 months to detect serum IgG antibodies. Results The incidence of adverse reactions after oral cholera vaccine was 3.26%. The positive rates of antibody at 0, 1, 2, and 8 months were 7.06%, 54.34%, 76.09% and 39.13% respectively. No cholera was found in 8 months epidemic. Conclusions After oral cholera vaccine, the level of serum antibody in peacekeeping officers and soldiers has been greatly increased, which has a certain preventive effect on cholera.