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目的:观察、比较3种通草类药材(通脱木、盘叶掌叶树、罗伞)和7种小通草类药材(喜马山旌节花、西南绣球①,②、棣棠花、穗序鹅掌柴、青荚叶、中国旌节花)的抗炎、解热作用及3种小通草药材(喜马山旌节花、西南绣球②、中国旌节花)的利尿作用,以期为该类药材的功效和临床应用、品种整理和质量研究提供药理学依据。方法:采用角叉菜胶致大鼠足肿胀、啤酒酵母(或角叉菜胶)致大鼠发热模型及大鼠代谢笼法等药理实验方法,观察比较不同药材水煎剂(8,4g/kg)灌胃给予大鼠后的抗炎、解热和利尿作用。结果:3种通草和7种小通草药材对大鼠角叉菜胶性足肿胀有不同程度的抑制作用,对啤酒酵母(或角叉菜胶)所致的大鼠发热模型表现出不同程度的解热作用,其中通草类药材中通脱木、盘叶掌叶树抗炎、解热作用为优;7种小通草类药材中喜马山旌节花和穗序鹅掌柴抗炎作用较强。3种小通草药材(喜马山旌节花、西南绣球②、中国旌节花)具有明显的利尿作用。结论:结果表明不同品种的通草和小通草类药材均具有不同程度的抗炎、解热和利尿作用,为该类药材的功效和临床应用、品种整理和质量研究提供了药理学依据
Objectives: To observe and compare the three kinds of herbicides (Tongmu, Cymbidium, and Umbrella) and 7 kinds of Herbal Medicinal Herbs (Hiyama flowers, southwestern hydrangea 1,2, flowers, spikes The anti-inflammatory and anti-pyretic effects of Schefflera schreberi, barley leaves, and Chinese knotted flowers) and the diuretic effects of 3 kinds of Xiao Tong herbs (Hiyama flowers, South-Western hydrangea, and Chinese knotted flowers) are expected to be The efficacy, clinical application, variety sorting and quality research of this kind of medicinal materials provide pharmacological basis. METHODS: Rat paw edema caused by carrageenan, febrile yeast model induced by beer yeast (or carrageenan), and rat metabolic cage method were used to observe and compare the decoctions of different herbs (8,4g/ Kg) Anti-inflammatory, antipyretic and diuretic effects after intragastric administration to rats. RESULTS: The three kinds of herbs and seven kinds of Xiaotong herbs had different degrees of inhibition on carrageenan foot swelling in rats, and showed different degrees of rat fever model caused by beer yeast (or carrageenan). Antipyretic effects, including through grass herbs in the off the wood, leaf palm tree leaf anti-inflammatory, antipyretic effect is excellent; 7 kinds of small through grass herbs in the Hibiscus hawthorn flower and ear sequence Schefflera strong anti-inflammatory effect. Three kinds of Xiaotong herbal medicines (Himashan Hawthorn Flower, Southwestern Hydrangea 2 and Chinese Lantern Festival Flower) have obvious diuretic effects. Conclusion: The results show that different species of Tongcao and Xiaotongcao herbs have different degrees of anti-inflammatory, antipyretic and diuretic effects, providing pharmacological basis for the efficacy and clinical application of the medicinal materials, variety sorting and quality research.