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从中国红参(Panax ginseng C.A.Meyer)中分离出十种单体(RG 1～10),用IR.MS(FD-MS.FAB-MS)、~(13)C-NMR以及化学方法等鉴定了化学结构,分别为20(R)-ginsenoside Rh,(RG-1),ginsenoside-Rg,(RG-2),20(R)-ginsenoside-Rg_2(RG-3),20(R)proto-panaxatriol(RG-4)以及人参皂甙Rg.(RG-5),—Re(RG-6)—Rd(RG-7),—RC(RG-8),—Rd_2(RG-9),—Rb,(RG-10);其中RG-1、RG-3、RG-4系首次从中国红参分离得到的人参皂甙成分。用薄层对照未炮制前的白参不含以上三种成分,这可能是红参与白参药理作用上差异的原因之一。
Ten monomers (RG 1～10) were isolated from Panax ginseng CAMeyer and identified by IR.MS (FD-MS.FAB-MS), 13C-NMR and chemical methods. The chemical structures were 20(R)-ginsenoside Rh, (RG-1), ginsenoside-Rg, (RG-2), 20(R)-ginsenoside-Rg_2(RG-3), 20(R)proto- Panaxatriol (RG-4) and ginsenoside Rg. (RG-5), -Re(RG-6)-Rd(RG-7), -RC(RG-8), -Rd_2(RG-9), -Rb (RG-10); of which RG-1, RG-3, and RG-4 are ginsenosides that have been isolated from Chinese red ginseng for the first time. The white ginseng before unconcocted with a thin layer of control does not contain the above three components, which may be one of the reasons for the involvement of red in the pharmacological effects of white ginseng.