CD4 4是近年来研究较多的与肿瘤转移密切相关的粘着分子之一。许多研究发现 CD4 4变异型( CD4 4V)在非何杰金淋巴瘤、结肠癌、胃癌、乳腺癌等多种肿瘤中表达明显升高 ,且与肿瘤的转移和浸润密切相关。本文采用逆转录 -聚合酶链反应 ( RT-PCR)研究了 CD4 4V在肾癌及癌旁组织中的 CD4 4 is one of the most closely studied adhesion molecules involved in tumor metastasis in recent years. Many studies have found that the CD4 4 variant (CD4 4V) expression in non-Hodgkin’s lymphoma, colon cancer, gastric cancer, breast cancer and other tumors were significantly increased, and closely related to tumor metastasis and invasion. In this paper, the use of reverse transcription - polymerase chain reaction (RT-PCR) of CD4 4V in renal cell carcinoma and adjacent tissues