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目的分析比较序贯与全程静脉应用抗生素在预防手术后感染的成本和效果,为合理使用抗菌药物,降低药品费用提供参考。方法采用成本-效果分析法对两组序贯给药法和两组全程静脉给药法进行分析。结果4组给药方法的有效率差异无统计学意义(P>0.05),两序贯给药组的成本效果比均小于两全程静脉给药组,而两序贯给药组之间的成本效果比差异无统计学意义(P>0.05)。结论手术后预防感染使用抗菌药时实施序贯给药,是有成本效果的。
Objective To compare and analyze the cost and effect of sequential and full intravenous antibiotics in preventing postoperative infection and provide references for rational use of antimicrobial agents and reduction of drug costs. Methods The cost-effect analysis method was used to analyze the two sequential administrations and the two intravenous administrations. Results There was no significant difference in the effective rates between the four groups (P> 0.05). The cost-effectiveness ratio of the two sequential administration groups was less than that of the two intravenous administration groups, while the cost between the sequential administration groups The difference was not statistically significant (P> 0.05). Conclusion It is cost effective to use sequential administration of antibacterials to prevent infection after surgery.