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为研究菖龙丹对沙土鼠脑缺血再灌注脑组织超氧化物歧化酶（ＳＯＤ）、丙二醛（ＭＤＡ）含量的影响。首先阻断沙土鼠双侧颈总动脉血流１０ｍｉｎ，造成缺血再灌注模型。术前术后予以菖龙丹灌胃。再灌注２４ｈ后，测定脑匀浆ＳＯＤ及 ＭＤＡ含量。结果：缺血再灌注后，脑匀浆ＭＤＡ明显升高，ＳＯＤ显著降低；菖龙丹给药组 ＭＤＡ含量下降，ＳＯＤ活性提高，差异显著。提示菖龙丹对缺血再灌注脑损伤有保护作用。
To study the effect of Qilongdan on the contents of superoxide dismutase (SOD) and malondialdehyde (MDA) in cerebral tissue of gerbils with cerebral ischemia-reperfusion. First of all, the blood flow of the common carotid artery was blocked for 10 minutes in the gerbil, resulting in ischemia-reperfusion model. Preoperative and postoperative patients were given Ganlongdan gavage. After 24 hours of reperfusion, SOD and MDA contents in brain homogenates were measured. Results: After ischemia and reperfusion, the MDA of brain homogenate was significantly increased and the SOD was significantly decreased. The content of MDA and the activity of SOD increased significantly in the treatment group. It is suggested that Pteridium has a protective effect on cerebral ischemia-reperfusion injury.