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目的:探讨脉压(PP)与高血压病心血管事件发生的关联性。方法:107例发生心血管事件患者列入研究组,131例单纯高血压患者列入对照组,对比所有患者个人及家庭病史、饮酒吸烟、身高体重情况,检测患者血压、血糖、高密度脂蛋白胆固醇(HDL-C)、甘油三脂(TG)、血清总胆固醇(TC)和PP值。结果:两组患者在年龄、病程、SBP、DBP和PP方面经统计学比较具有显著差异(P<0.05);研究组PP值在(60~80)mmHg间的患者比例(51.40%)明显高于其它取值范围(7.48%,28.04%,13.08%),60 mmHg患者的心血管疾病发生率最低(P<0.05)。结论:临床将PP控制在60 mmHg以下对高血压患者较安全。
Objective: To investigate the relationship between pulse pressure (PP) and cardiovascular events in hypertensive patients. Methods: A total of 107 patients with cardiovascular events were enrolled in the study group. One hundred and thirty-one patients with hypertension were included in the control group. The personal and family history, alcohol consumption, height and weight were compared among all patients. Blood pressure, blood glucose, high density lipoprotein Cholesterol (HDL-C), triglyceride (TG), serum total cholesterol (TC) and PP value. Results: There were significant differences in age, course of disease, SBP, DBP and PP between the two groups (P <0.05); the proportion of patients with study group PP between (60-80) mmHg (51.40%) was significantly higher In other ranges (7.48%, 28.04%, 13.08%), the incidence of cardiovascular disease was the lowest in 60 mmHg patients (P <0.05). Conclusion: The clinical control of PP below 60 mmHg is safer for patients with hypertension.