绿脓杆菌黑素(Melanin)合成菌株的报导最早见于1897年。产生黑素的绿脓杆菌可见于不同的疾病:女性生殖器炎症、脑膜炎、败血症、慢性肾盂肾炎,恶性肿瘤。这些菌常常不具有某些特有的种的特性,因而难于鉴定。目前,黑素的抗菌性质及其与抗菌的相互作用正被广泛研究。合成的黑素在试管内可抑制某些抗菌素的抗菌活性。某些真菌黑素、细菌黑素和合成黑素不具有抗菌性质。在过去文献中作者未找到关于绿脓杆菌黑素的抗菌性质的报导。本文报导了绿脓杆菌黑 The first reported strain of Melanin was found in 1897. Pseudomonas aeruginosa producing melanin can be found in different diseases: female genital inflammation, meningitis, sepsis, chronic pyelonephritis, malignant tumors. These bacteria often do not have some peculiar species characteristics, and therefore difficult to identify. At present, the antibacterial properties of melanin and its interaction with antibacterials are widely studied. Synthetic melanin inhibits the antibacterial activity of some antibiotics in vitro. Some fungal melanins, bacterial melanins and synthetic melanins do not have antimicrobial properties. The authors did not find reports on the antibacterial properties of Pseudomonas aeruginosa in the past literature. This article reports Pseudomonas aeruginosa black