论文部分内容阅读
本文观察了60例不同临床分期的高血压病患者血浆凝血(口恶)B_2(TXB_2,血栓素B_2)、6-酮-PGF+(1α)的变化,结果表明,高血压病各期TXB_2均明显升高,Ⅰ期高血压组6-酮-PGF_(1α)亦明显升高,TXB_2/6-酮-PGF_(1α)比值仅轻度增加;Ⅱ、Ⅲ期高血压组6-酮-PGF_(1α)则明显降低,TXB_2/6-酮-PGF_(1α)比值显著增加。组间比较:Ⅱ、Ⅲ期高血压组较Ⅰ期高血压组6-酮-PGF_(1α)显著降低,TXB_2/6-酮-PGF_(1α)比值明显增加。说明从高血压病初期到Ⅲ期,均有TXA_2、PGI_2的异常改变,这些变化可能与高血压的持续发展有关。
In this paper, we observed the changes of plasma B_2 (TXB_2, TXB2, 6-keto-PGF + (1α)) in 60 patients with different clinical stages of hypertension. The results showed that TXB_2 was significantly The level of 6-keto-PGF_ (1α) in group I was significantly increased, while the ratio of TXB_2 / 6-keto-PGF_ (1α) 1α) was significantly lower, TXB_2 / 6-keto-PGF_ (1α) ratio increased significantly. Compared between groups, the levels of 6-keto-PGF_ (1α) and the TXB_2 / 6-keto-PGF_ (1α) in group Ⅱ and Ⅲ were significantly higher than those in group Ⅰ. Description from the early stage of hypertension to stage Ⅲ, there TXA_2, PGI_2 abnormal changes, these changes may be related to the sustained development of hypertension.