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目的：探讨无创呼吸机对COPD合并Ⅱ型呼吸衰竭的临床疗效及护理方法。方法选取我院近3年收治的患者60例,随机分为A、B两组,B组给予常规治疗,A组在B组的基础上给予呼吸机通气治疗。结果治疗后,A组的SaO2显著高于治疗前,呼吸、心率显著低于治疗前；组间相比,A组的SaO2显著高于B组(﹤0.05),呼吸、心率则显著低于B组(﹤0.05)。治疗后,A组的PaO2显著高于治疗前,PaCO2显著低于治疗前；组间相比,A组的PaO2显著高于B组(﹤0.05),PaCO2则显著低于B组(﹤0.05)。结论无创正压通气是治疗COPD合并Ⅱ型呼吸衰竭的有效方法,能够改善患者的生命体征及动脉血气。“,”Objective To discuss the Clinical effect and nursing methods of non invasive mechanical ventilation on COPD patients with type.Methods 60 cases of COPD patients with type II respiratory failure of our hospital in recent 3 years were selected.According to the random number table,60 patients were divided into divided into A,B two groups,group B was given conventional treatment,and the A group was treated with ventilator ventilation based on the B group.Results After treatment,the SaO2 of A group was significantly higher than before treatment,compared to B group,the SaO2 of A group was significantly higher( <0.05),respiration and heart rate was significantly lower( <0.05).Conclusion Noninvasive positive pressure ventilation is an effective method to treat COPD with type II respiratory failure,which can improve the vital signs and arterial blood gas.