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经典的理论认为,肾素-血管紧张素系统是一个循环的内分泌系统。最近生物化学和分子生物学研究表明,在许多靶器官(包括:心脏、血管、脑、肾脏、肾上腺、卵巢和睾丸等)的局部存在肾素和血管紧张素原mRNA及其产物,靶细胞内的这种自动分泌一旁分泌系统对调节局部组织生理功能,稳定机体内环境起重要作用。我院从1987年起建立了研究心肌局部肾素-血管紧张素系统的动物实验、分离、提取、检测技术,研究了大鼠局部血管紧张素
The classic theory is that the renin-angiotensin system is a circulating endocrine system. Recent biochemical and molecular biological studies have shown that the presence of renin and angiotensinogen mRNA and its products, target cells in many target organs (including: heart, blood vessels, brain, kidneys, adrenals, ovaries and testes) The automatic secretion of this secretion system plays an important role in regulating the physiological functions of local tissues and stabilizing the environment in the body. Our hospital since 1987 to establish a study of myocardial renin - angiotensin system in animal experiments, isolation, extraction, detection technology to study the local angiotensin