论文部分内容阅读
1例52岁女性患者,因乳腺癌术后辅助化疗给予曲妥珠单抗220mg加入0.9%氯化钠注射液250ml静脉滴注,滴速为50滴/min。输入约30min时,患者出现寒战、胸闷、口唇发麻、呼吸困难,心率165次/min,血压199/99mm Hg。立即停止输液,行对症治疗。50min后上述症状消失,心率及血压恢复正常。21d后再次化疗,曲妥珠单抗110mg加入0.9%氯化钠注射液250ml静脉滴注,滴速30滴/min。5min后,患者再次出现过敏样症状。停药10min后症状消失。
A 52-year-old female patient received intravenous infusion of 250 ml of trastuzumab 220 mg plus 0.9% sodium chloride injection at a drip rate of 50 drops / min for postoperative adjuvant chemotherapy of breast cancer. Enter about 30min, the patient chills, chest tightness, numbness of the lips, difficulty breathing, heart rate 165 beats / min, blood pressure 199 / 99mm Hg. Immediate stop infusion, line symptomatic treatment. The symptoms disappeared after 50min, heart rate and blood pressure returned to normal. After 21d chemotherapy, trastuzumab 110mg 0.9% sodium chloride injection 250ml intravenous drip, drip rate 30 drops / min. After 5 minutes, the patient reappeared with allergic symptoms. Symptoms disappeared after 10 minutes of withdrawal.