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目的:观察替罗非班对冠状动脉介入无复流现象的治疗效果。方法:对冠状动脉介入术中出现无复流现象39例患者依次给予硝酸甘油、维拉帕米和替罗非班,观察靶血管前向血流的TIMI分级。结果:替罗非班明显改善TIMI血流,治疗无复流现象的有效率(28/33)明显优于硝酸甘油的有效率(4/39)和维拉帕米的有效率(2/35),差异有统计学意义(P<0.01)。结论:替罗非班对冠状动脉介入术中无复流现象有确切疗效。
Objective: To observe the therapeutic effect of tirofiban on coronary artery without reflow. METHODS: Ninety-three patients with no-reflow during coronary intervention were given nitroglycerin, verapamil, and tirofiban sequentially to observe the TIMI grade of the target vessel’s anterior blood flow. Results: Tirofiban significantly improved the TIMI flow, and the effective rate of no-reflow (28/33) was significantly better than that of nitroglycerin (4/39) and verapamil (2/35 ), The difference was statistically significant (P <0.01). Conclusion: Tirofiban has the exact effect on no-reflow phenomenon during coronary intervention.