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目的探讨液基薄层细胞学检测(TCT)联合阴道镜检查对宫颈癌筛查的价值。方法回顾性研究妇科门诊1 038例临床可疑患者进行宫颈癌筛查,其中536例做液基薄层细胞学检查联合阴道镜下宫颈活检(观察组),502例直接阴道镜下宫颈活检(对照组),以病理诊断为金标准,比较两组组织学诊断阳性符合率。结果观察组组织学诊断阳性符合率为72.01%,对照组为50.30%,两组比较差异有统计学意义(P<0.05)。结论液基薄层细胞学检查联合阴道镜活检可提高宫颈癌早期诊断率。
Objective To investigate the value of liquid-based cytology (TCT) combined with colposcopy in cervical cancer screening. Methods A retrospective study of 1 038 clinically suspected patients with gynecological outpatients was conducted for cervical cancer screening. Among them, 536 patients underwent liquid-based thin-layer cytology combined with colposcopic cervical biopsy (observation group) and 502 patients underwent colposcopic biopsy (control Group), pathological diagnosis as the gold standard, histological diagnosis of positive comparisons between the two groups. Results The positive coincidence rate of histological diagnosis was 72.01% in the observation group and 50.30% in the control group, the difference between the two groups was statistically significant (P <0.05). Conclusion Liquid-based thin-layer cytology combined with colposcopy biopsy can improve the early diagnosis of cervical cancer.