目的探讨宫颈环形电切术(LEEP)对妊娠结局和分娩方式的影响。方法采用回顾性病例对照研究,选择因宫颈上皮内瘤变(CIN)Ⅱ~Ⅲ而行宫颈环形电切术,于术后妊娠并分娩的31例产妇为研究组。按年龄、孕次、产次、经济收入相匹配的原则,选取同期分娩且孕前未行任何宫颈手术的产妇62例为对照组,2组均无并发症,观察2组间的早产儿发生率、胎膜早破发生率、分娩方式及新生儿体重等指标的差异。结果研究组早产率9.68%、胎膜早破发生率6.45%、剖宫产发生率41.94%、新生儿出生体重<2500 g者发生率6.45%;对照组早产率8.06%、胎膜早破发生率4.84%、剖宫产发生率38.71%、新生儿出生体重<2500 g者发生率4.84%,2组比较差异无统计学意义(P>0.05)。结论 LEEP可能对妊娠结局无不良影响。 Objective To investigate the effect of cervical ring electrosurgical excision (LEEP) on pregnancy outcome and delivery mode. Methods A retrospective case-control study was conducted. Cervical ring resection due to cervical intraepithelial neoplasia (CIN) Ⅱ ~ Ⅲ was selected. Twenty-one pregnant women with postpartum pregnancy and childbirth were selected as the study group. Based on the principle of matching age, pregnancy time, birth time and economic income, 62 maternal women who did not undergo any cervical surgery during the same period of pregnancy were selected as the control group. There were no complications in both groups. The incidence of preterm birth was observed between the two groups , The incidence of premature rupture of membranes, mode of delivery and neonatal weight and other indicators of difference. Results The premature birth rate was 9.68%, the incidence of premature rupture of membranes was 6.45%, the incidence of cesarean section was 41.94%, the incidence of neonates with birth weight <2500 g was 6.45%, that of control group was 8.06%, premature rupture of membranes Rate of 4.84%, cesarean section rate of 38.71%, neonatal birth weight <2500g were 4.84%, no significant difference between the two groups (P> 0.05). Conclusions LEEP may have no adverse effect on pregnancy outcome.