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目的:观察宫腔内直接放置卡孕栓用于减少剖宫产术中、术后出血量的临床效果。方法:选择120例有产后出血高危因素的剖宫产产妇,随机分为卡孕栓宫腔内给药组(研究组)与单纯缩宫素给药组(对照组A)、卡孕栓阴道给药组(对照组B)、卡孕栓直肠给药组(对照组C),每组各30例,观察4组剖宫产产妇术中、术后2 h出血量,用药后血压变化及不良反应情况。结果:研究组剖宫产术术中、术后2 h出血量均明显少于对照组A(P<0.01),研究组剖宫产术中出血量明显少于对照组B及对照组C(P<0.01);各组产妇用药术后血压变化差异均无统计学意义(P>0.05)。研究组无一例发生不良反应。结论:卡孕栓宫腔内给药法有减少剖宫产术中、术后出血量,且不良反应少。
Objective: To observe the clinical effect of intrauterine placement of carbamazepine directly to reduce the amount of bleeding after cesarean section. Methods: 120 cases of cesarean section with high risk of postpartum hemorrhage were randomly divided into intrauterine administration group (study group) and oxytocin injection group (control group A) (Control group B) and carbapenem rectal administration group (control group C), 30 cases in each group. The changes of blood pressure after operation, cesarean section postoperative 2 h, Adverse reactions. Results: In the cesarean section of the study group, the amount of hemorrhage 2 h after operation was significantly less than that of the control group A (P <0.01). The bleeding volume of the study group during cesarean section was significantly less than that of the control group B and the control group C P <0.01). There was no significant difference in blood pressure after maternal drug administration among all groups (P> 0.05). No case of adverse reactions in the study group. CONCLUSION: Intrauterine administration of carbamazepine reduces the amount of bleeding during and after cesarean section with less adverse reactions.