目的：增加对喉及下咽部少见肿瘤的认识，为临床积累资料。方法：回顾分析喉及下咽部少见恶性肿瘤６例的临床资料。结果：６例中４例表面黏膜光滑，术前活检困难；１例仅有咽部异物感，曾误诊为慢性咽炎；经治疗，随访２～３年无复发４例，０．５～１．５年复发２例。结论：术前活检宜在直接喉镜下深取或术中作快速冰冻检查；如患者仅有咽部异物感，应常规检查下咽部；治疗以手术为主，切除范围应足够大，有的患者术后需加以放疗。 OBJECTIVE: To increase the awareness of rare tumors of larynx and hypopharynx for the purpose of accumulating clinical data. Methods: The clinical data of 6 cases of rare malignant tumor in larynx and hypopharynx were retrospectively analyzed. Results: The surface mucosa of 4 cases was smooth and the biopsy was difficult before operation. Only 1 case had pharyngeal foreign body sensation and had been misdiagnosed as chronic pharyngitis. After treatment, there was no recurrence in 2 to 3 years (4 cases, 0.5 to 1). 5 cases of recurrent in 2 cases. Conclusions: Preoperative biopsy should be performed under direct laryngoscope or rapid intraoperative frozen examination; if the patient has only throat foreign body sensation, the hypopharynx should be routinely checked; the operation should be performed mainly and the resection scope should be large enough to have Of patients need to be treated with radiotherapy.