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目的观察舒血宁注射液治疗慢性肺源性心脏病(慢性肺心病)急性加重期的疗效。方法将164例患者随机分为舒血宁组和对照组,每组82例,全部病例均采取通畅气道、控制感染、纠正心衰等常规治疗,治疗组同时应用舒血宁注射液,观察治疗前、后血液流变学、血气分析变化。结果治疗后舒血宁组的血液流变学数据明显下降,组间差异有显著性(P<0.01)。舒血宁组治疗后PaO2升高显著(P<0.01),PaCO2下降(P<0.05);对照组治疗后PaO2升高(P<0.05),PaCO2显著下降(P<0.05)。舒血宁组与对照组治疗后比较PaO2升高明显(P<0.01),PaCO2下降(P<0.05)。结论舒血宁注射液能明显改善肺心病患者的症状、体征,疗效显著。
Objective To observe the therapeutic effect of Shuxuening injection in acute exacerbation of chronic cor pulmonale (chronic cor pulmonale). Methods 164 patients were randomly divided into Shuxuening group and control group, with 82 cases in each group. All the patients were given routine treatment of unobstructed airway, infection control and heart failure correction. The treatment group was treated with Shuxuening injection simultaneously Hemorheology before and after treatment, blood gas analysis changes. Results After treatment, the blood rheology data of Shuxuening group decreased significantly, with significant difference between the two groups (P <0.01). PaO2 significantly decreased (P <0.01) and PaCO2 decreased (P <0.05). PaO2 increased (P <0.05) and PaCO2 decreased (P <0.05) in control group. Shuxuening group and control group after treatment PaO2 increased significantly (P <0.01), PaCO2 decreased (P <0.05). Conclusion Shuxuening injection can significantly improve the symptoms and signs of patients with cor pulmonale, the curative effect is remarkable.