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目的探讨左氧氟沙星联合替硝唑治疗盆腔炎的临床疗效及安全性。方法 120例盆腔炎患者,根据随机数字表法分为实验组和对照组,每组60例。对照组采用氧氟沙星联合甲硝唑治疗,实验组采用左氧氟沙星联合替硝唑治疗。观察两组患者的临床疗效及不良反应发生情况。结果实验组临床痊愈率及总有效率明显高于对照组,不良反应发生率明显低于对照组,差异均有统计学意义(P<0.05)。结论左氧氟沙星联合替硝唑治疗盆腔炎的临床疗效明显优于氧氟沙星联合甲硝唑,其抗菌活性及总有效率明显提高,不良反应发生率降低,安全可靠,值得临床推广应用。
Objective To investigate the clinical efficacy and safety of levofloxacin plus tinidazole in the treatment of pelvic inflammatory disease. Methods A total of 120 patients with pelvic inflammatory disease were divided into experimental group and control group according to random number table method, with 60 cases in each group. The control group was treated with ofloxacin and metronidazole, and the experimental group was treated with levofloxacin plus tinidazole. The clinical efficacy and adverse reactions of the two groups were observed. Results The clinical cure rate and total effective rate in the experimental group were significantly higher than those in the control group, and the incidence of adverse reactions was significantly lower than that in the control group (P <0.05). Conclusions Levofloxacin and tinidazole are superior to ofloxacin and metronidazole in the treatment of pelvic inflammatory disease. The antibacterial activity and total effective rate of levofloxacin combined with tinidazole are obviously improved. The incidence of adverse reactions is reduced, which is safe and reliable. It is worthy of clinical application.