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目的：探究临床治疗肝硬化并发胆囊结石患者的过程中，应用腹腔镜治疗，分析其临床治疗效果，评价其安全性，为临床肝胆治疗奠定基础。方法自我院2014年6月~2015年12月收治的64例肝硬化并发胆囊结石患者，对比患者应用不同治疗方案进行治疗，观察临床疗效。结果予以不同治疗方案后，对试验组患者采用腹腔镜治疗的各项临床指标均显著优于对照组，如出血量、手术、术后排气及住院时间等，差异显著(P＜0.05)。对试验组患者采用腹腔镜治疗的术后7 d各项生化指标显著优于对照组，如TBIL、ALT、PT等，差异显著(P＜0.05)。且试验组患者采用腹腔镜治疗的并发症发生率（3.12%，1/32）显著低于对照组（18.75%，6/32），差异显著(P＜0.05)。结论临床治疗肝硬化并发胆囊结石患者的过程中，腹腔镜治疗可显著改善患者的各项临床指标，加速患者的康复，具有较好的安全性，应广泛推广。“,”Objective To explore the clinical treatment of liver cirrhosis complicated with gallstones, laparoscopic treatment, analyze the clinical treatment effect, to evaluate the safety and treatment and lay the foundation for the clinical hepatobiliary.Methods 64 cases of liver from June 2014 self hospital in~2015 December during the hardening of cholecystolithiasis patients, were treated with different treatment regimens were compared the application and clinical observation. Results Different treatments, the test group were treated by laparoscopic treatment of the clinical indicators were significantly better than the control group, such as bleeding, surgery, postoperative exhaust time and hospitalization time, significant difference (P<0 .05). The test group was treated with laparoscopic treatment of postoperative 7 days control group was better than that of biochemical indexes, such as TBIL, ALT, PT, significant difference (P<0.05). And the test group were treated by laparoscopic treatment of the complication rate (3.12%, 1/32) was significantly lower than the control group (18.75%, 6/32), significant difference (P<0.05).Conclusion The clinical treatment of liver cirrhosis complicated with gallstones,laparoscopic treatment can significantly improve clinical indexes of patients,accelerate rehabilitation,with better security,should be widely promoted.