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目的 通过对广州市2016年霍乱病例的调查分析, 为霍乱防治提供科学依据.方法 按照《霍乱防治手册》 (第六版) 和《广东省霍乱疫情现场调查处理指引》对霍乱疫情进行规范处理.结果 共采样40宗, 其中病人粪便1宗、肛试子4宗、密切接触者9宗、环境拭子13宗、水样5宗、海水产品8宗, 检出病人前期粪便和肛拭子阳性各一份, 其余标本检测结果均为阴性.结论 综合判定病人为霍乱弧菌 (O1群稻叶型) 感染, 属轻型病例.“,”Objective To provide the scientific basis for cholera prevention and control through the investigation and analysis of cholera cases in Guangzhou in 2016. Methods According to the Guidelines for Cholera Prevention and Control (Sixth Edition) and the Guidelines for Investigation and Handling of Cholera in Guangdong Province, standardize the treatment of cholera epidemic. Results A total of 40 samples were collected, including 1 stool, 4 anal testimonies, 9 close contact person, 13 environmental swabs, 5 water samples and 8 seawater products. Cholera virus detections were positive in pre-fecal samples and anal swabs, and the remaining specimens were negative. Conclusion After the outbreak, urban CDC intervened in epidemiological investigation and epidemic disposal quickly, and there was no recurrence of cases. According to the clinical manifestations, laboratory test results and epidemiological survey, refer to the “cholera diagnostic criteria” (WS 289-2008), the patient was determined as vibrio cholerae (O1 group rice leaf type) infection, and was a light case.