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当前,鼻咽癌(NPC)Ⅰ期放疗的5年生存率达80％～90％以上。由于NPC常侵犯颅底与颅神经,而在CT问世之前常用不大敏感的平片与多体层照片,故习惯于把蝶窦包括在照射体积内。Lenz指出,即使照片阴性,也不能排除颅底早期侵蚀,故照射也包括了垂体与中颅窝的大脑(颞叶),且所给治疗性剂量并不难。随着患者生存期延长,因而放射后期的下丘脑-垂体轴机能障碍与颞叶坏死并发症也表现
At present, the 5-year survival rate of stage Ⅰ radiotherapy for NPC is 80% -90%. As NPC often violated the skull base and cranial nerves, but before the advent of CT commonly used not sensitive plate and multi-level photos, it is customary to include the sphenoid sinus in the irradiation volume. Lenz pointed out that even if the photo negative, can not rule out early skull erosion, it also includes the irradiation of the pituitary and the cranial fossa of the brain (temporal lobe), and given the therapeutic dose is not difficult. With the prolongation of patient survival, the late-emergent hypothalamic-pituitary axis dysfunction and temporal lobar necrosis complications also manifest