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肺癌侵袭和转移是多基因、多步骤共同作用的结果,协同促进了细胞癌变、侵袭和转移。其中肿瘤转移抑制基因结构和功能异常,导致对肿瘤转移表型的失调控,最终导致肿瘤转移。近年来细胞水平和组织水平的研究表明nm23 H1为肿瘤转移抑制基因 (tumormetastasissuppressorgenes),
Invasion and metastasis of lung cancer is a multi-gene, multi-step results of the joint action, synergistically promote cell carcinogenesis, invasion and metastasis. Tumor metastasis suppressor gene structure and function abnormalities, leading to dysregulation of tumor metastasis phenotype, eventually leading to tumor metastasis. In recent years, cell level and tissue level studies have shown that nm23 H1 is a tumor metastasis suppressor gene (tumor metastasuppressorgenes)