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随着空气污染日趋严重及吸烟人群逐渐扩大,肺癌的发生率及病死率在我国逐年上升,小细胞肺癌(SCLC)约占肺癌患者的20%,病情进展快,生存期短[1]。手术和化学治疗及放射治疗是治疗恶性肿瘤的三大手段[2]。对于小细胞肺癌治疗目前临床以静脉化疗为主,化疗药物在杀伤癌细胞的同时,难免损伤正常的细胞、组织等。长期以来,白细胞减少症是恶性肿瘤患者在放化疗过程中或放、化疗后的严重并发症之一,
With the worsening of air pollution and the gradual expansion of smoking population, the incidence and mortality of lung cancer have been increasing year by year in China. Small cell lung cancer (SCLC) accounts for about 20% of patients with lung cancer. The disease progresses rapidly and has a short survival period [1]. Surgery and chemotherapy and radiation therapy are the three major means of treatment of malignant tumors [2]. For the treatment of small cell lung cancer in the current clinical intravenous chemotherapy, chemotherapy drugs in the killing of cancer cells, inevitably damage normal cells, tissues and so on. For a long time, leukopenia is one of the serious complications of patients with malignant tumors during radiotherapy and chemotherapy or radiotherapy and chemotherapy,