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目的 探讨更昔洛韦联合干扰素滴眼液治疗小儿单疱病毒性角膜炎的疗效。方法 就小儿单疱毒性角膜炎的发病特点进行分析 ,同时分析了更昔洛韦和干扰素滴眼液的药理作用 ,以及联合用药的临床价值。结果 更昔洛韦与干扰素滴眼液联合用药后有效率为 97 62 % ,明显高于其它报道 ,经随访半年至一年基本无复发 ,视力均有不同程度提高。结论 更昔洛韦联合干扰素滴眼液对小儿单疱病毒性角膜炎有明显的治疗效果 ,具有促进其角膜上皮生长 ,增加小儿抵抗力等优点 ,无过敏和毒性反应 ,为临床治疗HSK提供了一个新的途径。
Objective To investigate the curative effect of ganciclovir combined with interferon eye drops on herpes simplex keratitis in children. Methods The incidence of unilateral herpes simplex keratitis was analyzed. The pharmacological effects of ganciclovir and interferon eye drops and the clinical value of combination therapy were also analyzed. Results Ganciclovir and interferon combined eye drops effective rate was 97.62%, significantly higher than other reports, followed up for six months to a year basically no recurrence, visual acuity increased to varying degrees. Conclusion Ganciclovir combined with interferon eye drops on children with herpes simplex keratitis has a significant therapeutic effect, with its promotion of its corneal epithelial growth, increased resistance in children and other advantages, no allergic and toxic reactions for the clinical treatment of HSK A new way.