Avant Immunotherapeutics公司正在进行肽类抗胆固醇酯转移蛋白疫苗CETi-1用于治疗HDL胆固醇低下的II期临床研究。该疫苗能刺激针对胆固醇酯转移蛋白（CETP）抗体的产生。CETP的主要作用是保持HDL和LDL胆固醇之间的平衡，因而，可以假设CETP的抑制可能会增加HDL胆固醇的水平。I Avant Immunotherapeutics is conducting Phase II clinical trials of the peptide anti-cholesteryl ester transfer protein vaccine CETi-1 for the treatment of HDL cholesterol. The vaccine stimulates the production of cholesterol ester transfer protein (CETP) antibodies. The main role of CETP is to maintain the balance between HDL and LDL cholesterol, so it can be assumed that inhibition of CETP may increase the level of HDL cholesterol. I