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目的 研究老年原发性高血压 ( EH)患者脉压 ( PP)与颈动脉扩张性、粥样硬化的关系。方法 选择 2 13例老年高血压患者 ,其中男性 12 1例 ,女性 92例 ,平均年龄 ( 66.8± 6.2 )岁。将所有病例按 PP值分成四组 ,应用 B型超声对颈动脉进行扫查 ,测量内径、内膜中层厚度 ( IMT)及粥样斑块。然后比较各 PP组肱动脉在不同状态下的管径变化情况。结果 PP与 IMT呈正相关关系 ,其相关性强于收缩压 ( SBP)、舒张压 ( DBP)、平均动脉压 ( MAP)。随 PP增大 ,颈动脉发生严重颈动脉斑块的比率明显增大 ,扩张性降低 ,差异均有显著性。结论 PP增大与老年高血压患者颈动脉扩张性降低、粥样硬化关系密切。
Objective To study the relationship between pulse pressure (PP) and carotid dilatation and atherosclerosis in elderly patients with essential hypertension (EH). Methods Twenty-two elderly hypertensive patients were selected, including 12 males and 92 females, with an average age of 66.8 ± 6.2 years. All cases were divided into four groups according to the PP value. The carotid artery was scanned with B ultrasound to measure the inner diameter, the intima-media thickness (IMT) and the plaque. Then compare the PP group brachial artery diameter changes under different conditions. Results There was a positive correlation between PP and IMT. The correlation was stronger between SBP, DBP and MAP. With the increase of PP, carotid artery serious carotid artery plaque was significantly increased, dilatation decreased, the difference was significant. Conclusions The increase of PP is associated with decreased carotid dilatation and atherosclerosis in elderly hypertensive patients.