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目的:测算子宫颈癌患者生命质量,为临床实践中子宫颈癌治疗方案的选择和子宫颈癌患者生命质量的提高提供参考依据。方法:选取276名子宫颈癌患者为研究对象,所有病例均经病理学确诊。采用欧洲五维度健康量表(EQ-5D)评价子宫颈癌患者生命质量。结果:子宫颈癌CIN2及以下患者量表指数(Index)评分为(0.916 5±0.013 3)分、视觉模拟尺度(VAS)评分为(86.23±11.13)分,接近正常女性人群评分。但随着子宫颈癌病理和临床分期的提高,Index评分逐渐降低,分别由0.916 5分降至0.872 3分和由0.913 8分降至0.868 9分;VAS评分亦逐渐降低,分别由83.09分降至64.97分和86.23分降至65.37分。不同的治疗方法后子宫颈癌患者的生命质量亦有差异。Index得分由低到高依次为:子宫颈癌根治术+化疗、单纯化疗、子宫颈癌根治术、子宫全切术、子宫颈锥切术。VAS得分由低到高依次为:子宫颈癌根治术+化疗、子宫颈癌根治术、单纯化疗、子宫全切术、子宫颈锥切术。除子宫颈癌根治术与单纯化疗略有交叉外,其他治疗方案得分顺序相同。结论:随着子宫颈癌患者病情的加重,生命质量不断降低,提示子宫颈癌早期诊断和治疗可以显著改善子宫颈癌患者的生命质量。实施不同治疗方案的子宫颈癌患者的生命质量不同,提示患者生命质量也应作为临床实践中治疗方案的选择依据。
Objective: To evaluate the quality of life of patients with cervical cancer and provide a reference for the selection of treatment options for cervical cancer in clinical practice and the improvement of life quality of patients with cervical cancer. Methods: 276 cervical cancer patients were selected as the research object, all cases were confirmed by pathology. The quality of life of cervical cancer patients was evaluated by the European Five-Dimensional Health Scale (EQ-5D). Results: The score of CIN2 and below in cervical cancer patients was (0.916 5 ± 0.013 3) points and the visual analog scale (VAS) score was 86.23 ± 11.13 points, which was close to the score of normal female population. However, as the pathological and clinical stage of cervical cancer increased, the Index score gradually decreased from 0.916 5 points to 0.872 3 points and 0.913 8 points to 0.868 9 points; VAS score also gradually decreased from 83.09 points To 64.97 points and 86.23 points to 65.37 points. The quality of life of patients with cervical cancer after different treatment methods are also different. Index scores from low to high were as follows: radical mastectomy + chemotherapy, chemotherapy alone, radical mastectomy, hysterectomy, cervical conization. VAS scores from low to high were as follows: radical mastectomy + chemotherapy, cervical cancer radical mastectomy, chemotherapy alone, hysterectomy, cervical conization. In addition to cervical cancer radical surgery and chemotherapy slightly cross, the other treatment programs score the same order. Conclusion: With the aggravation of cervical cancer patients, the quality of life is decreasing, suggesting that early diagnosis and treatment of cervical cancer can significantly improve the quality of life of patients with cervical cancer. Different quality of life of patients with cervical cancer who implement different treatment options, suggesting that the quality of life of patients should also be used as the basis for the selection of treatment options in clinical practice.