论文部分内容阅读
目的:探讨ABCD3-Ⅰ评分法对短暂性脑缺血发作(TIA)患者进展脑梗死的风险预测价值。方法:收集187例以TIA为首发症状的患者,并且按照ABCD3-Ⅰ评分法分为低危组、中危组和高危组,观察30 d和90 d脑梗死发生率,并采用Logistic回归分析TIA进展为脑梗死的危险因素。结果:30 d内脑梗死和90 d内脑梗死发生率高危组明显高于中危组和低危组,有显著性差异(P<0.01)。双重TIA发作(OR=7.364;95%CI:1.536~35.305)、同侧颈动脉狭窄≥50%(OR=6.562;95%CI:2.841~15.156)、磁共振DWI出现高信号(OR=6.215;95%CI:2.783~13.879)是TIA进展为脑梗死独立的危险因素。预测90 d脑梗死方面,ABCD3-Ⅰ的ROC曲线下面积明显大于ABCD2和ABCD3。结论:ABCD3-I评分法能很好预测TIA进展为脑梗死的风险,可作为常规应用于临床,指导TIA危险分层评价和治疗。
Objective: To investigate the predictive value of ABCD3-Ⅰ score in predicting the progression of cerebral infarction in patients with transient ischemic attack (TIA). Methods: A total of 187 patients with TIA as the first symptom were collected and divided into low-risk group, moderate-risk group and high-risk group according to ABCD3-Ⅰ score. The incidence of cerebral infarction at 30 days and 90 days was observed. Logistic regression analysis was used to analyze TIA Progress is a risk factor for cerebral infarction. Results: The incidence of cerebral infarction within 30 days and the incidence of cerebral infarction within 90 days were significantly higher than those of moderate-risk group and low-risk group (P <0.01). (OR = 6.264; 95% CI: 1.536-35.305), ≥50% ipsilateral carotid stenosis (OR = 6.562; 95% CI: 2.841-15.156) 95% CI: 2.783 ~ 13.879) is an independent risk factor for progression of TIA to cerebral infarction. For the 90-day cerebral infarction, the area under the ROC curve of ABCD3-Ⅰ was significantly larger than that of ABCD2 and ABCD3. Conclusion: The ABCD3-I score can predict the TIA progression to cerebral infarction. It can be used routinely in clinical practice to guide the TIA risk stratification evaluation and treatment.