建立了 2 羟基喹口恶啉的高效液相色谱分析方法 ,流动相 :pH =5 ,甲醇 +水 (V/V) =30 +70 ,在UV - 2 80nm下用外标法进行测定 ,方法精密度为 0 2 5 ,变异系数为 0 2 5 % ,回收率在 99 6%～ 10 0 .9%之间 A HPLC method for the determination of 2 - hydroxyquiketoxine was established. The mobile phase was pH = 5, methanol + water (V / V) = 30 +70 and the UV - 280 nm was determined by external standard method The precision was 0 2 5, the coefficient of variation was 0 2 5%, the recovery was between 99 6% ~ 10 0 .9%