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乙胺碘呋酮(amiodrone)又叫安律酮。它作为抗心律失常药进入80年代后才逐渐在我国基层医疗单位应用。由于它较其它抗心律失常药有很多优点,故以前对此临床效果报道较多,而专题论术其副作用的文章尚属乏见。为了更合理地使用此药,现将其副作用简述如下:1.心血管系统:(1)可造成窦性心动过缓而不易被阿托品所逆转,使 Q—T间期延长。(2)可诱发传导方面的障碍,其机理也与它的治疗机理密切相关。(3)可导致新的心律失常的发生,其发生者尤见于静脉给药者。如法国心脏病学会11例中5例死亡,均为静脉给药。
Amiodrone is also known as antiodone. As an anti-arrhythmic drug, it entered the 1980s and was gradually applied in primary medical units in our country. Because of its many advantages over other anti-arrhythmic drugs, it has previously reported more clinical effects, while the thematic papers the side effects of the article is still rare. In order to more reasonable use of this drug, its side effects are summarized as follows: 1. Cardiovascular system: (1) can cause sinus bradycardia and is not easily reversed by atropine, Q-T interval prolongation. (2) can induce conduction disorders, the mechanism is also closely related to its treatment mechanism. (3) can lead to the occurrence of new arrhythmias, the occurrence of which is particularly found in intravenous donors. As in the French Society of Cardiology in 11 cases of 5 deaths, are intravenous.