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目的:探讨本科护生职业自我效能的现状，分析不确定压力对护生职业自我效能的影响。方法:采取整群便利抽样法，2020年4月10 —17日，选取浙江省4所高校1 526名护理本科生为研究对象。采用护生一般情况问卷、护生职业自我效能问卷（PSQNS）及不确定压力问卷对其进行横断面调查。采用多重线性回归分析护生职业自我效能的影响因素。共发放问卷1 526份，回收有效问卷1 474份，有效回收率为96.6%。结果:1 474名本科护生PSQNS总分为（91.10±14.11）分，条目均分为（3.37±0.52）分，得分率为67.48%，处于中等水平。多重线性回归分析结果显示，护理专业喜爱程度、不确定压力、在校学业成绩、选择护理专业原因及家庭经济状况是本科护生职业自我效能的影响因素（n P<0.05），可解释33.4%的变异。n 结论:本科护生的职业自我效能有待提升；护理教育者可以通过降低护生的不确定压力，提高其职业自我效能。“,”Objective:To explore the current status of undergraduate nursing students' professional self-efficacy, and analyze the influence of uncertainty stress on nursing students' professional self-efficacy.Methods:From April 10 to 17, 2020, the cluster convenience sampling was used to select 1 526 nursing undergraduates from four universities in Zhejiang Province as the research object. The cross-sectional survey was conducted with the General Information Questionnaire for Nursing Students, Professional Self-efficacy Questionnaire for Nurse Students (PSQNS) and the Uncertain Stress Questionnaire. Multiple linear regression was used to analyze the influencing factors of professional self-efficacy of nursing students. A total of 1 526 questionnaires were issued, and 1 474 valid questionnaires were returned with the effective response rate of 96.6%.Results:Among 1 474 undergraduate nursing students, the total PSQNS score was (91.10±14.11) , and the item average score was (3.37±0.52) , and the score rate was 67.48%, which was in the middle level. The results of multiple linear regression analysis showed that the preference for the nursing major, uncertainty stress, academic achievement in school, reasons for choosing the nursing major, and family economic status were the influencing factors of professional self-efficacy of undergraduate nursing students with statistical differences (n P<0.05) , which could explain 33.4% of the variation.n Conclusions:The professional self-efficacy of undergraduate nursing students needs to be improved. Nursing educators can improve their professional self-efficacy by reducing the uncertainty stress of nursing students.