吸烟对轻度支气管哮喘患者吸入激素疗效的影响

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目的观察吸烟对轻度支气管哮喘患者吸入激素疗效的影响.方法对不吸烟(18例)及吸烟(17例)的支气管哮喘患者每日吸入二丙酸倍氯米松500μg治疗4周,治疗前后进行肺功能测定及气道反应性试验,用药过程中监测呼气峰流速(peak expiratory flow,PEF).结果不吸烟组患者治疗后的清晨PEF、睡前PEF、FEV1%及气道反应性均较治疗前改善(P<0.05).而吸烟组患者在治疗前后上述指标却变化不大(P>0.05).结论吸烟能明显减弱支气管哮喘患者吸入激素的疗效,支气管哮喘患者应积极戒烟以取得较好的
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支气管哮喘是慢性呼吸道疾病,要想很好控制症状,提高病人的生存质量,必须规范吸入糖皮质激素治疗.临床发现许多患者虽然知道一些哮喘防治知识,但能坚持疗程规范治疗的并不多.
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