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目的探讨卵巢鳞形细胞癌的临床病理特征。方法对1例卵巢囊性成熟性畸胎瘤恶变成鳞形细胞癌的临床、病理和免疫学表型进行观察、分析及文献复习。结果患者临床表现为腹痛。镜下见成熟鳞形细胞与鳞形细胞癌细胞相移行。免疫组化瘤细胞34βE12和CK14阳性,ER、PR、HRE-2均阴性。结论卵巢囊性成熟性畸胎瘤恶变成鳞形细胞癌是一种极其少见的现象。其诊断依赖于组织病理学、免疫组化,并须结合其临床资料。
Objective To investigate the clinicopathological features of ovarian squamous cell carcinoma. Methods The clinical, pathological and immunological phenotypes of one malignant ovarian cystic teratoma with malignant transformation to squamous cell carcinoma were observed, analyzed and reviewed. Results The clinical manifestations of patients with abdominal pain. Microscopically seen mature squamous cell and squamous cell carcinoma phase shift. Immunohistochemical tumor cells 34βE12 and CK14 positive, ER, PR, HRE-2 were negative. Conclusion Ovarian cystic maturity teratoma malignant transformation into squamous cell carcinoma is an extremely rare phenomenon. Its diagnosis depends on histopathology, immunohistochemistry, and must be combined with its clinical data.