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目的观察在常规药物洋地黄、利尿剂、血管紧张素转换酶抑制剂(ACEI)治疗的基础上加用β受体阻滞剂卡维地洛治疗慢性充血性心力衰竭(CHF)并心房颤动患者的临床疗效。方法120例慢性CHF并心房颤动患者(除外风湿性心脏瓣膜病患者)随机分成两组:对照组常规给予洋地黄、利尿剂、卡托普利治疗;观察组在常规治疗的基础上加用卡维地洛治疗,治疗16周观察心功能、运动耐量、心率、血压的变化情况。结果观察组与对照组的有效率分别为93.9%和86.6%(P<0.05),观察组无严重副反应的发生。结论在常规抗CHF药物治疗基础上加用卡维地洛治疗慢性CHF并心房颤动是安全有效的。
Objective To observe the effects of carvedilol, a traditional Chinese medicine, on the treatment of chronic congestive heart failure (CHF) and atrial fibrillation (ACEI) on the basis of conventional digitalis, diuretic and angiotensin converting enzyme inhibitor (ACEI) The clinical efficacy. Methods 120 patients with chronic CHF and atrial fibrillation (except rheumatic heart valve disease) were randomly divided into two groups: the control group routinely given digitalis, diuretic, captopril treatment; the observation group on the basis of conventional treatment with a card Vedlotol treatment, treatment of 16 weeks observed cardiac function, exercise tolerance, heart rate, blood pressure changes. Results The effective rates of the observation group and the control group were 93.9% and 86.6% (P <0.05), respectively. There was no serious adverse reaction in the observation group. Conclusion It is safe and effective to add carvedilol to chronic CHF and atrial fibrillation on the basis of conventional anti-CHF drug therapy.