作者等用七烯大环内酯类抗菌素在狗及大白鼠体内进行了一系列的口服毒性试验发现,口服杀念珠菌素(Candicidin)20毫克/公斤,30多天后,对动物的前列腺有显著缩小的生理影响。作者在产生良性前列腺增生症的狗中,给予不同的多烯大环内酯类抗菌素进行口服治疗,分别以5、10、20毫克/公 The authors conducted a series of oral toxicity studies using hepcidin macrolides in dogs and rats and found that oral administration of Candicidin 20 mg / kg over 30 days had significant effects on the prostate of the animals Shrinking physiological effects. The authors gave different polyene macrolide antibiotics for oral treatment in dogs with benign prostatic hyperplasia, treated with 5, 10, 20 mg /