冠心病的发生存在着性别差异 ,绝经后妇女冠心病的发生率急剧上升 ,在应用雌激素治疗后 ,冠心病的发生率明显下降 ,提示雌激素对心血管具有保护作用。本文结合近年来的文献 ,综述了雌激素对冠心病发病因素的影响及产生心血管保护作用的机制 There are gender differences in the occurrence of coronary heart disease, the incidence of coronary heart disease in postmenopausal women increased dramatically, the incidence of coronary heart disease decreased significantly after estrogen treatment, suggesting that estrogen has a protective effect on cardiovascular. In this paper, combined with recent literature, reviewed the impact of estrogen on the incidence of coronary heart disease and cardiovascular protection mechanism