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作者探讨了尘肺患者的持续性蛋白尿的出现率和肾脏损害的发病经过。在所检查的283例中发现有持续性蛋白尿者13例(4.6%),从组织学上看多为肾小球肾炎。肾脏损害可随发热和胸膜炎出现并类似狼疮肾炎或间质性肾炎。在非定型的胶原病活动期可发生肾脏损害。此外,在体液免疫功能持续亢进情况下,可出现快速进行性肾炎。以上结果提示粉尘接触工人,由于粉尘对免疫细胞的作用,有发生肾脏损害的可能性。
The authors examined the incidence of persistent proteinuria and the pathogenesis of kidney damage in patients with pneumoconiosis. In the examination of 283 cases found in persistent proteinuria in 13 cases (4.6%), mostly from the histological view of glomerulonephritis. Kidney damage can occur with fever and pleurisy and is similar to lupus nephritis or interstitial nephritis. Kidney damage can occur during non-stylized collagen disease activity. In addition, in the case of persistent humoral immune function, rapid progressive nephritis may occur. The above results suggest that dust exposure to workers, due to the role of dust on immune cells, the possibility of kidney damage.