论文部分内容阅读
本文就人体α—干扰素(INF)与放疗对肺和肿瘤组织的作用,对有选择性的小细胞肺癌(SCLC)患者身上进行了研究。患者必须是初治且病灶局限。共分两组:7例INF高量组病人,先接受高剂量的INF(800×10~6Iu iV×5),然后低剂量维持(6×10~6Iu im2/W),局部病灶辅以间隔放疗(55Gy/20F/7W)。5例低量INF组,一开始就用低剂量的INF(6×10~6Iu im Qd),并配合每日两次分割放疗,总量为44Gy/40F/4W。两组均有4例行全脑预防性照射,高量组因脑转移有3例全脑照射。对播散到胸腔以外的病例,停INF,加用化
In this paper, the role of human interferon-alpha (IFN) and radiotherapy in lung and tumor tissues was studied in patients with selective SCLC. The patient must be initially treated and the lesion limited. Two groups were divided into two groups: 7 patients with INF high dose group received high-dose INF (800×10~6Iu iV×5), and then maintained at low dose (6×10~6Iu im2/W) with local lesions supplemented by intervals. Radiotherapy (55Gy/20F/7W). In 5 low-dose INF groups, low-dose INF (6×10~6Iu im Qd) was used at the beginning, combined with twice daily split radiotherapy, for a total of 44 Gy/40 F/4 W. There were 4 cases of whole brain prophylactic irradiation in both groups, and 3 cases of whole brain irradiation were due to brain metastases in the high-level group. For cases spread outside the chest, stop INF and add