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安体舒通是传统的弱效利尿剂,它的化学结构与醛固酮相似,能竞争远曲小管和皮质部集合管细胞浆内醛固酮受体,故可拮抗醛固酮的留钠排钾作用,促进钠和钾的排出而产生利尿,因钠-钾交换机制受抑,钾的排出减少。近年来,作为老药新用,它在内科疾病的治疗中发挥了不可替代的作用,因而?
Spironolactone is a traditional weak-effect diuretic, its chemical structure and aldosterone similar, can compete distal convoluted tubule and cortical collection cytoplasm aldosterone receptor, it can inhibit the role of aldosterone sodium retention row of potassium to promote sodium And potassium excretion diuretic due to suppression of sodium - potassium exchange mechanism, reducing the discharge of potassium. In recent years, as a new use of old drugs, it plays an irreplaceable role in the treatment of medical diseases, therefore?