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报告1例皮肤软纤维瘤基础上发生的鳞状细胞癌。患者女,65岁。左手臂皮肤袋状突起10年余,迅速增大6个月。皮肤科检查:左上臂伸侧有一2.5 cm×2 cm×2 cm暗红色不规则球形肿块,质中等,肿块随肢体活动可轻度扭转。皮损大体病理:球形肿块剖面呈灰白色,有蒂;组织病理:肿物表面多灶性坏死,瘤细胞呈巢团状向纤维组织内浸润,细胞核大、深染、多形,蒂部被覆皮肤基本完整,表皮角化过度,棘层肥厚,纤维组织增生部分变性,皮下见癌细胞浸润。诊断为皮肤软纤维瘤继发鳞状细胞癌。
One case of squamous cell carcinoma that reported on the basis of skin fibroma was reported. Female patient, 65 years old. Left arm skin pouch protrusion more than 10 years, the rapid increase of 6 months. Dermatology examination: the left upper arm extensor has a 2.5 cm × 2 cm × 2 cm dark red irregular spherical mass, medium mass with mild physical activity can be reversed. Skin lesions gross pathology: spherical mass was gray, pedunculated; histopathology: multifocal necrosis of the tumor surface, the tumor cells nest nuclei infiltrated into the fibrous tissue, large nuclei, deep staining, pleomorphic, pedicle covered skin Basically complete, epidermal hyperkeratosis, stratum hypertrophy, partial degeneration of fibrous tissue proliferation, subcutaneous see cancer cell infiltration. Diagnosis of cutaneous fibroma secondary squamous cell carcinoma.