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本文研究了抗心磷脂抗体（ACA）、狼疮抗凝因子（LA）、生物学假阳性梅毒血清学试验（BFP-STS）在系统性红斑狼疮（SLE）中的临床意义。还探讨了前列环素（PGI_2）和血栓素（TXA_2）在ACA的致病机理中的作用和它们的临床意义。应用ELISA法检测了42例SLE患者和36例正常人血清标本的IgG、IgM、IgA型ACA。发现ACA在SLE病例中的阳性率为54.7％。其中IgG的阳性率为45.2％，IgM为38.1％，IgA为11.9％。LA在SLE病例中的阳性率为9.5％，BFP-STS的阳性率为4.7％。结果提示：在SLE病例中，IgM和IgA型ACA与血栓有显著关系。ACA还与SLE病例的活动性、血小板减少有显著关系。但ACA与习惯性
This article studies the clinical significance of anticardiolipin antibody (ACA), lupus anticoagulant (LA) and biological false positive syphilis serological test (BFP-STS) in systemic lupus erythematosus (SLE). The roles of prostacyclin (PGI_2) and TXA_2 in the pathogenesis of ACA and their clinical significance were also explored. Serum samples from 42 patients with SLE and 36 normal controls were assayed for IgG, IgM and IgA ACA by ELISA. The positive rate of ACA in SLE cases was found to be 54.7%. The positive rate of IgG was 45.2%, IgM was 38.1% and IgA was 11.9%. The positive rate of LA in SLE cases was 9.5% and the positive rate of BFP-STS was 4.7%. The results suggest that, in SLE cases, IgA and IgA ACA and thrombosis have a significant relationship. ACA is also associated with SLE activity, thrombocytopenia. But ACA and habitual