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目的:探讨腹膜后低度恶性肌纤维母细胞肉瘤(LGMS)的临床特征及其诊治。方法:回顾性分析2000年1月～2010年5月我院收治3例经病理确诊的腹膜后LGMS患者的临床资料。其中男2例,女1例,患者平均发病年龄40.6(28～70)岁。并结合文献复习探讨本病的临床特征、组织病理学特点和诊治、预后。结果:本组3例均行完整的手术切除,切缘阴性。病理确诊3例均为腹膜后LGMS,随访2年未见复发。结论:腹膜后LGMS临床罕见,术前易误诊,确诊依赖于病理检查。综合分析临床资料,提高对此病的临床认识是避免误诊的关键。完整的手术切除和严密随访以避免复发。
Objective: To investigate the clinical features, diagnosis and treatment of retroperitoneal low grade myofibroblastic sarcoma (LGMS). Methods: The clinical data of 3 patients with pathologically confirmed retroperitoneal LGMS in our hospital from January 2000 to May 2010 were retrospectively analyzed. Including 2 males and 1 females, the average age of onset of patients 40.6 (28 to 70) years old. Combined with the literature review to explore the clinical features of the disease, histopathological features and diagnosis and treatment, prognosis. Results: All the three cases underwent complete surgical resection with negative margins. The pathological diagnosis of 3 cases were retroperitoneal LGMS, no recurrence 2 years follow-up. CONCLUSIONS: Retroperitoneal LGMS is rare in clinical practice, and is easily misdiagnosed before surgery. Diagnosis depends on pathological examination. Comprehensive analysis of clinical data to improve the clinical understanding of the disease is the key to avoiding misdiagnosis. Complete surgical resection and follow-up to avoid recurrence.