目的探讨下呼吸道绿脓杆菌（ＰＡ）感染菌株的血清分型及其与临床的关系。方法采用ＶｉｔｅｋＡｍｓＧＮＩ鉴定卡作ＰＡ株鉴定；ＧＮＳＧＡ卡作抗生素敏感试验；２０型一套诊断血清作ＰＡ血清分型。结果１０１株中分离出１４个血清型，总分型率为８４２％。分型率较高的是Ｐ６（２３７％）、Ｐ１（１３９％）、Ｐ３（１０９％）；１６株未获分型（１５８％）。未获分型株中菌落呈粘液型者占６３％，这些患者年龄偏大，感染较重，病死率较高（１３％）。体外抗生素敏感试验以对氨基糖甙类最为敏感。结论绿脓杆菌血清学分型可作为鉴别感染同源性，监测院内感染，分析菌型分布地区特点的重要手段。体外药敏结果与血清学分型无明显关系。未获分型菌株感染有其特殊性 Objective To investigate the serotyping of clinical isolates of Pseudomonas aeruginosa (PA) infection in lower respiratory tract and its clinical significance. Methods Vitek  AmsGNI identification card for PA strain identification; GNS  GA card for antibiotic susceptibility testing; 20 sets of diagnostic serum for PA serotyping. Results Of the 101 isolates, 14 serotypes were isolated with a total typing rate of 842%. P6 (237%), P1 (139%), P3 (109%) were higher than those in the other three strains. 16 strains were not typed (158%). 63% of non-typed strains were mucoid, and these patients were older, more infected and had a higher case fatality rate (13%). In vitro antibiotic susceptibility tests are most sensitive to aminoglycosides. Conclusion The serological typing of Pseudomonas aeruginosa can be used as an important means to identify the homology of infection and monitor the nosocomial infection and analyze the characteristics of the geographical distribution of the bacteria. In vitro susceptibility results and serological classification no significant relationship. Unrecorded strain infection has its particularity