目的 探讨狼疮性肾炎尿毒症的可逆性。方法 在15年中,对37例狼疮性肾炎已开始进行透析的患者,给予积极的激素和环磷酰胺治疗。结果 83.8％的患者脱离了透析,停止透析的平均时间为40.6±21.5个月,停止透析半年以上的血肌酐值平均为179.36±88.24μmol/L。结论 需要透析的狼疮性肾炎患者,并不等于终末期肾病,在有适应症时,经积极治疗,肾衰有逆转的可能。 Objective To investigate the reversibility of uremia in patients with lupus nephritis. Methods In 15 years, 37 patients with lupus nephritis who had started dialysis were given active hormones and cyclophosphamide. Results 83.8% of the patients were out of dialysis, the average time to stop the dialysis was 40.6 ± 21.5 months, and the serum creatinine value of stopping dialysis for more than six months was 179.36 ± 88.24μmol / L on average. Conclusion Patients with lupus nephritis who need dialysis do not equal to end-stage renal disease. In the case of indications, after active treatment, renal failure may be reversed.