曼氏血吸虫病肝纤维化在程度上差别很大,有些病人很轻,有些病人则严重到形成肝硬变。纤维化过程有认为是由于病人发生自身免疫反应而引起的。本文目的在于研究血吸虫病肝纤维化的各阶段是否存在自身抗体反应,借以解释纤维化反应的易变性。同时, Schistosoma mansoni Hepatic fibrosis varies widely in severity, with some patients very mild and some patients severe until cirrhosis. Fibrosis is thought to be caused by the patient’s autoimmune response. The purpose of this article is to investigate whether there is an autoantibody response in each stage of liver fibrosis in schistosomiasis to explain the variability of fibrotic responses. Simultaneously,