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原发性胆汁性肝硬化属自身免疫性疾病，常伴血脂紊乱，但这种血脂紊乱常与疾病的心血管事件无关。他汀类药物及非诺贝特不但可调节原发性胆汁性肝硬化的血脂水平，对其预后也有一定益处。“,”Primary biliary cirrhosis belongs to autoimmune diseases,and often occurs with dyslipidemia.However, numberous evi-dence have demonstrated that“altered lipid profiles” in primary biliary cirrhosis is not associated with cardiovascular events.Stains and/or fenofibrate does not only regulate lipid levels, but also improve prognosis in patients with primary biliary cirrhosis.