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目的益气活血方治疗对老年2型糖尿病脑梗死恢复期患者负性情绪和生活质量及血糖的影响。方法选取2015年1月~2016年10月我院110例气虚血瘀型2型糖尿病合并脑梗死恢复期患者,随机分为观察组和对照组,各60例,对照组接受西医常规治疗,观察组在对照组治疗的基础上加用自拟益气活血方治疗,疗程均为14 d。观察2组临床疗效、神经功能缺损程度、焦虑抑郁情绪、生活质量、空腹血糖(FBG)、餐后2 h血糖(2h PG)及糖化血红蛋白(Hb Alc)。结果治疗后观察组总有效率、神经受损程度、运动功能及独立程度显著优于对照组(P<0.05);治疗后,观察组生活质量高于对照组(P<0.05);2组治疗后FBG、2h PG、Hb Alc水平均较治疗前显著降低,且观察组上述糖代谢指标的改善情况显著优于对照组(P均<0.05);治疗后观察组焦虑、抑郁情绪评分显著低于对照组(P<0.05);2组治疗期间均未发现严重的药物相关的不良事件。结论益气活血方能有效降低老年气虚血瘀型2型糖尿病脑梗死恢复期患者血糖水平,促进神经功能的修复,改善运动情况、生活质量及焦虑抑郁情绪,值得推广。
Objective To investigate the effects of Yiqi Huoxue Recipe on negative emotions, quality of life and blood glucose in convalescent patients with type 2 diabetic cerebral infarction. Methods From January 2015 to October 2016, 110 cases of type 2 diabetes mellitus with type 2 diabetes mellitus and convalescence of cerebral infarction in our hospital were randomly divided into observation group and control group, 60 cases in each group. The control group received routine western medicine treatment and observation Group based on the treatment of the control group plus self-Yiqihuoxue Fang treatment, treatment were 14 d. The clinical efficacy, neurological deficit, anxiety and depression, quality of life, fasting blood glucose (FBG), postprandial 2h PG and Hb Alc were observed. Results After treatment, the total effective rate, nerve damage, motor function and independence of the observation group were significantly better than those of the control group (P <0.05). After treatment, the quality of life of the observation group was higher than that of the control group (P <0.05) The levels of FBG, 2h PG and Hb Alc in the observation group were significantly lower than those before treatment, and the improvement of glucose metabolism index in the observation group was significantly better than that in the control group (all P <0.05). After treatment, the anxiety and depression scores of the observation group were significantly lower Control group (P <0.05). No serious drug-related adverse events were found during the two groups. Conclusion Yiqi Huoxue Fang can effectively reduce blood glucose levels in elderly patients with type 2 diabetes mellitus with cerebral infarction at the early stage of Qi deficiency and blood stasis, promote the repair of neurological function, improve the exercise status, quality of life and anxiety and depression, which deserves promotion.