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欲启动肠免疫反应,抗原就必须突破肠上皮屏障,与其下的免疫效应细胞接触。覆盖于集合和孤立淋巴滤泡圆丘部的上皮中含有一种特殊细胞——M细胞。其位于免疫机制传入枝的前沿,特异地为大分子物质输送提供方便,籍此,使肠腔内抗原可与上皮间、上皮下淋巴细胞及巨噬细胞接触。M细胞具有输送抗原大分子的能力,并为病原微生物选择性穿透肠上皮屏障提供场所。病原菌一旦突破上皮可启动免疫反应,可在局
To start the intestinal immune response, the antigen must break through the intestinal epithelial barrier and contact with the immune effector cells beneath it. Cover the collection and isolated lymphoid follicles in the epithelium contains a special cell - M cells. It is located in the forefront of the immune system into the branches, specifically for the delivery of macromolecules to facilitate, so that the intestinal cavity antigen with epithelial, subepithelial lymphocytes and macrophages contact. M cells have the ability to deliver antigenic macromolecules and provide a place for pathogenic microorganisms to selectively penetrate the intestinal epithelial barrier. Pathogens once the breakthrough epithelium can start the immune response can be bureau