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乙醇是人们喜用的饮料,消费量正在不断上升。乙醇在肝脏中经醇脱氢酶作用后产生乙醛。乙醇和乙醛都能引起严重的生理学和临床上的后果。一、致畸性乙醇是人体的致畸物质,能诱发酒精胚胎疾病(AE)。AE有种种发育和智力的缺陷,如生长迟缓,小头畸形,智力迟钝,活动过度,典型的面部异常——朝天鼻、下颌骨发育不全等。心力衰竭、生殖器、关节和手掌的皱痕也很常见。据推测在酒精中毒慢性期的母亲所生的小儿约40%有先天的AE。AE是人类最常
Ethanol is a beverage that people like to use, and consumption is rising. Ethanol produces acetaldehyde in the liver after alcohol dehydrogenase action. Both ethanol and acetaldehyde can cause serious physiological and clinical consequences. First, teratogenicity Ethanol is the body’s teratogenic substances, can induce alcohol embryo disease (AE). AE has a variety of developmental and intellectual deficiencies, such as growth retardation, microcephaly, mental retardation, hyperactivity, typical facial abnormalities - astronomical nose, mandibular hypoplasia. Wrinkles on heart failure, genitalia, joints and palms are also common. It is estimated that about 40% of infants born to mothers with chronic alcoholism have congenital AEs. AE is the most common in humans